Extranodal N/K cell non-Hodgkin lymphoma nasal: An atypical case report
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Abstract
Introduction: Extranodal NK/T cell lymphoma (ENKTL) is a rare subtype of non-Hodgkin lymphoma Epstein-Barr virus associated. The pathogenesis of these lesions is not completely known. Objectives: To present an atypical case of nasal extranodal NK T-cell lymphoma. Materials and methods: We present the case of a 37-year-old patient with a diagnosis of extranodal nasal NK/T cell lymphoma with clinical symptoms and radiological images, which looks like a vascular tumor. Pre-surgical embolization was performed due to the high vascularity found on the tomography. The lesion was completely resected endoscopically, the patient received chemotherapy and radiotherapy, currently in remission with a two-year follow-up. Discussion: NK/T cell lymphomas are rare sinonasal tumors. Radiologically, they are locally invasive with extension to adjacent structures; they do not usually present as hypervascularized lesions. Conclusions: The detection of these tumors represents a challenge. Early diagnosis confers a better prognosis and response to treatment.
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Este artículo es publicado por la Revista Acta de Otorrinolaringología & Cirugía de Cabeza y Cuello.
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eISSN: 2539-0856
ISSN: 0120-8411
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References
van Doesum JA, Niezink AGH, Huls GA, Beijert M, Diepstra A, van Meerten T. Extranodal Natural Killer/T-cell Lymphoma, Nasal Type: Diagnosis and Treatment. Hemasphere. 2021;5(2):e523. doi: 10.1097/HS9.0000000000000523
Yamaguchi M, Suzuki R, Oguchi M. Advances in the treatment of extranodal NK/T-cell lymphoma, nasal type. Blood. 2018;131(23):2528-2540. doi: 10.1182/blood-2017-12-791418
Jeong SH. Extranodal NK/T cell lymphoma. Blood Res. 2020;55(S1):S63-S71. doi: 10.5045/br.2020.S011
Harabuchi Y, Takahara M, Kishibe K, Nagato T, Kumai T. Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Basic Science and Clinical Progress. Front Pediatr. 2019;7:141. doi: 10.3389/fped.2019.00141
Akbar M, Clasen-Linde E, Specht L. Extranodal NK/T-cell lymphoma, nasal type, with extranasal presentation - a case report and a review of the literature. Acta Oncol. 2020;59(12):1480- 1487. doi: 10.1080/0284186X.2020.1795250
Tse E, Kwong YL. The diagnosis and management of NK/T-cell lymphomas. J Hematol Oncol. 2017;10(1):85. doi: 10.1186/ s13045-017-0452-9
Asano N, Kato S, Nakamura S. Epstein-Barr virus-associated natural killer/T-cell lymphomas. Best Pract Res Clin Haematol. 2013;26(1):15-21. doi: 10.1016/j.beha.2013.04.002
Allen PB, Lechowicz MJ. Management of NK/T-Cell Lymphoma, Nasal Type. J Oncol Pract. 2019;15(10):513-520. doi: 10.1200/JOP.18.00719
Kim SJ, Jung HA, Chuang SS, Hong H, Guo CC, Cao J, et al. Extranodal natural killer/T-cell lymphoma involving the gastrointestinal tract: analysis of clinical features and outcomes from the Asia Lymphoma Study Group. J Hematol Oncol. 2013;6:86. doi: 10.1186/1756-8722-6-86
Mohd Ramli SS, Husain S, Wong YP. Extranodal NK/T cell lymphoma, nasal type: a rare diagnosis with common nasal presentation. BMJ Case Rep. 2021;14(6):e236436. doi: 10.1136/bcr-2020-236436