Association between the nutritional status of the pediatricpatient with juvenile recurrent respiratory papillomatosisand the clinical severity of their disease in a tertiarypediatric hospital between 2014-2020
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Abstract
Introduction: Juvenile Onset Recurrent Respiratory Papillomatosis (RRP) is the most common benign neoplasm in pediatric airways. Its management is difficult due to the need for multiple surgeries and the lack of curative therapy. Objectives: Establish the association between the nutritional status of children with RRP and the clinical severity of the disease. Materials and methods: Observational, retrospective, and descriptive study. Patients under 18 years of age with a diagnosis of RRP undergoing papilloma resection surgery at the National Institute of Pediatrics (INP), in Mexico City, between 2014 and 2020 were included. Results: 49 patients with RRP (25 women) were included, with a total of 123 surgical events. 62% of the patients had malnutrition without finding statistical significance with the severity of the disease (p = 0.087). Neither age at diagnosis, breastfeeding, nor birth weight had a statistical relationship with the severity of RRP. Being between 2 and 5 years old and the presence of a tracheostomy increases the probability of requiring more interventions per year and a shorter surgical interval (p = 0.02 and 0.014, respectively). Discussion: The prevalence of malnutrition in our series was high. No association was found between malnutrition or obesity with the severity of RRP. Avoiding tracheostomy as much as possible and a conservative surgical technique may be predictors of better results. Conclusions: No significant relationship was found between nutritional status and the severity of the disease.
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